Try to perform this at least once prior to reaching level 6, so as to force opponents out of the lane due to the threat of dying to Shadow Assault.
Talon is a hard champion to catch. Use Rake to slow pursuers, and Shadow Assault for the stealth and high movement speed. Change your path direction during stealth to juke and confuse your enemies. But keep in mind that the enemies can see where your blades travel when your stealth ends. So using the ability just to run can sometimes be better than running into the enemy jungle while trying to juke the enemies.
Cutthroat can be used to ambush enemies behind thin walls, if they are close enough and you have line of sight. Alternatively, you can use Cutthroat on a minion near an enemy champion for a quick entry into battle.
Noxian Diplomacy resets the autoattack timer, so use this ability after autoattacking to gain 2 hits in succession.
Shadow Assault can be used both defensively or offensively. It can be used as either a tool for chasing an escaping champion or escaping a gank.
It is difficult to utilize the movement speed of Shadow Assault to its fullest due to the small range of the radius, however. It is more likely the movement speed will be helpful to quickly get in range of a target to use Cutthroat on than simply running around should you wish to hit an enemy with Shadow Assault twice.
One way to ensure Shadow Assault's return hits your target is to use Cutthroat, immediately ending the stealth and positioning yourself such that the blades are guaranteed to hit.
Champion basic move combo requires him to activate Shadow Assault then closing the gap with Cutthroat which will devastate an enemy. If this does not completely annihilate an enemy continue with Rake to chase an enemy and if they still have not died, finish them with Noxian Diplomacy.
Noxian Diplomacy does not reveal stealthed champs in a usual way (as Sonic WaveLee Sin and Tempest, etc.).The target will leave a blood trail which can be helpful if facing champs with short stealth abilities (Vayne, Shaco). Also you can use it on champion to prevent him or her from hiding in bush.
When you are ganking/chasing enemy that has Flash or a similar escape tool (Ezreal, Gragas etc.) don't use your Cutthroat immediately, but simply run near him until he wastes his ability. However, be careful when he can jump over walls as you need vision of them to blink to them with Cutthroat.
The Brutalizer is an excellent early purchase for Talon, providing armor penetration and cool down reduction. It also builds into one of his core items, The Black Cleaver. Talon can quickly apply The Black Cleaver stacks to his target; Rake applies 2 stacks if it connects on both hits, while Shadow Assault applies a stack per cast (2 stacks total), and both spells can hit multiple targets. Additionally, being an AD caster, Talon values cooldown reduction and any armor penetration he can get, making The Black Cleaver an extremely efficient item on him.
Another powerful mid-late-game purchase for Talon is a Last Whisper. Not only it provides a nice amount of attack damage but also adds 35% armor penetration. Along with 3 point in Devastating Strikes [[Devastating Strikes|]] Mastery, Talon can achieve a total of 39% armor penetration.
Despite providing a large amount of attack damage, Infinity Edge is not a crucial or optimal purchase for Talon, as he does not rely on auto attacks as much as other melee champions. Combined with Youmuu's Ghostblade, however, Talon will have a 40% crit chance; the two items are very powerful only if Talon is ahead.
For a more burst-oriented build, Sheen can be surprisingly powerful early game by adding damage to Noxian Diplomacy and providing a bit more Mana. While its AP will go to waste, it can later transition into a more powerful Trinity Force and provide a wide array of stats and its Passive adds even more damage to Noxian Diplomacy.
If you have trouble in lane with sustain and think that potions are not enough for you, an early Vampiric Scepter or Doran's Shield are recommended. Scepter can be used later to build other Life Steal items that can greatly benefit Talon.
The Bloodthirster is the more common upgrade from Vampiric Scepter. It grants a rather large amount of AD provided it remains stacked. It's the best option to add damage all around, but if Talon is getting focused, it may be difficult to keep it full.
Ravenous Hydra is another excellent choice with solid stats. Cleave applies The Black Cleaver Passive and Crescent adds even more burst to Talon. A solid option for wave clearing and more team fight presence.
Talon is regarded as a counter to conventional Mages due to his silence, so Mercury's Treads is an excellent choice when fulfilling this role. Not only it provides magic resistance but also provides Tenacity which is excellent against teams with heavy crowd control.
Guardian Angel is a great purchase if ahead, as it makes Talon harder to kill and may deter the enemy team from focusing him.
Frozen Mallet triggers Mercy with every successful hit (NOTE: first hit will add slow, but won’t trigger passive). It provides utility, health, and some damage.
Other unconventional items like Randuin's Omen and Banshee's Veil are extremely situational and do decrease Talon's damage output drastically, but can also provide a great increase of survivability for Talon.
With Spirit of the Elder LizardTalon can focus more on split pushing. One of the strategies utilized consists on getting Boots of Mobility along with the previously mentioned and rush to the lanes, clear the waves with Rake, and rotate to another lane, trying to apply pressure constantly.
Talon is fairly squishy and vulnerable to harassment during the laning phase. Use this to your advantage but be aware that his Cutthroat and Rake can easily turn the engagement in his favor.
When playing as a Mage, Seeker's Armguard can provide a great amount of defense early game, decreasing Talon's damage substantially.
Champion reliance on burst damage is a heavy weakness against targets he can't quickly kill. Fighter champions tend to beat Talon, being durable enough to survive his combo and do enough damage to kill Talon afterwards - fighters with innate sustainability abilities in particular will survive Champion combo and then just heal themselves back up.
It is recommended to engage Talon when you think his Shadow Assault is on cooldown as it is his only escape mechanism.
Watch out for his Noxian Diplomacy and Cutthroat combo. It can deal significant damage and combined with Rake and his passive Mercy will deal significant amounts of damage within a few hits. Zone him when you can and press the advantage.